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What mysteries might a time-lapse of a single cell unlock, and how might it transform our understanding of disease and the body’s most granular processes—over the long term and in real time, to fuel new medicines? On Thursday, a powerhouse academic trio of [the Allen Institute](https://alleninstitute.org/), the [Chan Zuckerberg Initiative](https://chanzuckerberg.com/) (CZI), and the [University of Washington](https://www.uwmedicine.org/) announced the [Seattle Hub for Synthetic Biology](https://seattlehub.org/) (SEAHub) to take on that exact groundbreaking work: a collaborative to develop biotechnologies that create a historical biological record down to the single cell level and give scientists clues on when and how to intervene against burgeoning diseases. The science at the heart of SEAHub is a foundation for future discovery in the life sciences, says Rui Costa, a brain scientist, molecular biologist, and CEO and president of the Allen Institute—the nonprofit neuroscience and cell-biology research behemoth created by Microsoft cofounder Paul Allen in 2003 and key contributor to a [milestone “brain atlas”](https://www.fastcompany.com/90968493/scientists-largest-map-brain-alzheimers-parkinsons) mapping the inner-workings of the brain published last month—in an interview and guided tour of its Seattle headquarters with _Fast Company_ leading up to the institute’s 20-year anniversary Thursday. ![](https://images.fastcompany.net/image/upload/w_1200,c_limit,q_auto:best/wp-cms/uploads/2023/12/i-2-90994686-research-hub-cells.jpg) ![](https://images.fastcompany.net/image/upload/w_1200,c_limit,q_auto:best/wp-cms/uploads/2023/12/i-3-90994686-research-hub-cells.jpg) Inside the Allen Institute, researchers map the responses of human brain cells. \[Photos: courtesy of the author\] “Can you imagine if you take a cell, and you’d have a little recorder of how many inflammations or infections I had?” says Costa. “Or what did my body experience using the cell’s natural sensors? So, through the intelligent genomic design of a few cells, you could have live recorders of your history.” That technology, in turn, means that you can take a spontaneous response or a mutation at the genetic level and capture its effect on a cell. From that cellular effect, you can climb up to an effect on your body, such as, say, painful inflammation that might indicate an immune system disease—the kind of thing your doctor would notice when you visit the clinic with those symptoms. “I could say, hey, about one year ago, there was a large inflammatory response in your organism, you know, something happened here,” explains Costa. “Of course, _you_ don’t have awareness of that, but there are ways our body can record things that happened.” In lay terms, the implication is, scientists and drug developers would have powerful new tools to see exactly how a cell changes over time and the moment that spurs that biological event—a real-time crystal ball, giving them a glimpse at, not just the best biological targets, but the best biological _moments_ to intervene before a disease can take root. Executives from the Allen Institute and CZI, and lead scientists from UW Medicine who will be leading the Seattle Hub for Synthetic Biology, compare the effort to a “smart watch” for the genome that has the potential to revolutionize drug development strategies and foster untold future discovery. “Currently, when biologists take measurements, we’re limited to either observing how a few things change over time with a microscope or to measuring everything, but only at the moment in time that we break open the cell,” said Jay Shendure, executive director of the new hub and a medical scientist and professor of genome sciences at UW Medicine, in a statement. “With the kind of genomic smart watch that we’re aiming to build, one could recover the full autobiography of each cell rather than only the last page.” Priscilla Chan, cofounder and co-CEO of CZI, draws similar comparisons and their implications for our understanding of genetics, cells, disease, and their interplay with our environments. “By developing new technologies to measure and understand the history of our cells over time, including how they are impacted by the environment around them, genetic mutations, and other factors, we can expand scientists’ understanding of what happens at the cellular level when we go from healthy to sick, and help pinpoint the earliest causes of disease,” said Chan in a statement announcing the research hub. The democratic nature of the synthetic biology hub’s work is key for Costa, who believes the true excitement lies not just in the technology, but in the quixotic quest for scientific discovery and collaboration. “Discovery changes the world. So, the sharing of knowledge is empowering people,” he says.
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The CEO of [technology giant Nvidia](https://apnews.com/article/nvidia-trillion-artificial-intelligence-ai-chips-c2e5e41634dc4049209d4e1eba3836d8) said Friday that he views Malaysia as a potential hub for artificial intelligence “manufacturing,” though he did not confirm the chipmaker is in talks with a local conglomerate to set up AI data centers in the Southeast Asian country. Jensen Huang, Nvidia’s founder and CEO, told reporters in Kuala Lumpur that the Malaysian conglomerate YTL Corp. could play an important role in setting up AI data centers. Speaking at a media roundtable, Huang did not confirm reports that Nvidia is in talks with YTL, whose interests span utilities and telecommunications, cement, construction and property development. But he said that “YTL is an extraordinary company and has an incredible leadership and legacy.” Malaysia “is a very important hub for SEA’s computing infrastructure. It requires access to land, facilities, power, which is extraordinarily important,” he said. “I think YTL could play a great role in that.” Malaysia’s expertise in packaging, assembly, and other aspects of manufacturing make it well suited for the manufacturing of [artificial intelligence](https://apnews.com/hub/artificial-intelligence), Huang said. He said Nvidia was working with 80 AI startups in the country. “Here in Malaysia, the data center infrastructure layer of computing, which is one of the most important parts of the AI and the cloud, is very successful here,” Huang said. Southeast Asia will likely be a hub for AI computing because countries need their own AI data centers to refine and transform data into valuable information. Old data processing centers were designed to hold data files and run applications. AI requires use of each place’s culture, language, values, literature, and common sense, Huang said. “I don’t know plans of every region well, but I have great confidence that Southeast Asia is going to be a very important technology hub. It’s already quite excellent at packaging and assembly and battery manufacturing. It’s already very good at many aspects of the technology supply chain,” he said.[](https://popup.taboola.com/en/?template=colorbox&utm_source=associatedpress-apnews&utm_medium=referral&utm_content=rec-reel-2n5-a-2:Mid%20Article%20Reco%20Reel%20Slider:)
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The CEO of chipmaker Nvidia views Malaysia as a potential hub for artificial intelligence “manufacturing.” December 8, 2023, 5:30 AM ![Nvidia CEO and co-founder Jensen Huang attends a media round table event at a hotel in Kuala Lumpur, Malaysia Friday, Dec. 8, 2023. (AP Photo/Vincent Thian)](https://i.abcnewsfe.com/a/e3833fe1-1957-4f56-b25d-e47a7527b6cc/wirestory_a55209db56cdd3f85d2b7ea06516cc5d_16x9.jpg?w=992) Nvidia CEO and co-founder Jensen Huang attends a media round table event at a hotel in Kuala Lumpur, Malaysia Friday, Dec. 8, 2023. (AP Photo/Vincent Thian) KUALA LUMPUR, Malaysia -- The CEO of technology giant Nvidia said Friday that he views Malaysia as a potential hub for [artificial intelligence](https://abcnews.go.com/alerts/ArtificialIntelligence) “manufacturing,” though he did not confirm the chipmaker is in talks with a local conglomerate to set up AI data centers in the Southeast Asian country. Jensen Huang, Nvidia’s founder and CEO, told reporters in Kuala Lumpur that the Malaysian conglomerate YTL Corp. could play an important role in setting up AI data centers. Speaking at a media roundtable, Huang did not confirm reports that Nvidia is in talks with YTL, whose interests span utilities and telecommunications, cement, construction and property development. But he said that “YTL is an extraordinary company and has an incredible leadership and legacy.” Malaysia “is a very important hub for SEA’s computing infrastructure. It requires access to land, facilities, power, which is extraordinarily important,” he said. “I think YTL could play a great role in that.” Malaysia’s expertise in packaging, assembly and other aspects of manufacturing make it well suited for the manufacturing of artificial intelligence, Huang said. He said Nvidia was working with 80 AI startups in the country. “Here in Malaysia, the data center infrastructure layer of computing, which is one of the most important parts of the AI and the cloud, is very successful here,” Huang said. Southeast Asia will likely be a hub for AI computing because countries need their own AI data centers to refine and transform data into valuable information. Old data processing centers were designed to hold data files and run applications. AI requires use of each place's culture, language, values, literature and common sense, Huang said. “I don’t know plans of every region well, but I have great confidence that Southeast Asia is going to be a very important technology hub. It’s already quite excellent at packaging and assembly and battery manufacturing. It’s already very good at many aspects of the technology supply chain," he said.
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More than 1,100 unionized DHL Express workers walked off the job at Cincinnati/Northern Kentucky International Airport (CVG), a critical logistics hub for the package delivery company, during the busiest time of the year ByWYATTE GRANTHAM-PHILIPS AP business writer December 8, 2023, 11:51 AM ![A protester sits near a supply table during a protest at Cincinnati/Northern Kentucky International Airport near the DHL Express Hub Friday, Dec. 8, 2023, in Erlanger Ky. More than 1,000 union members at DHL walked off the job at Cincinnati/Northern Kentucky International Airport, a critical logistics hub for the package delivery company, during the busiest time of the year. The Teamsters say they are protesting unfair labor practices at the DHL Express hub. (AP Photo/Carolyn Kaster)](https://i.abcnewsfe.com/a/f23666ba-800e-4b2d-b0fe-fedd511fedfd/wirestory_cc353c574e7978e74c5391412ab9c16b_16x9.jpg?w=992) A protester sits near a supply table during a protest at Cincinnati/Northern Kentucky International Airport near the DHL Express Hub Friday, Dec. 8, 2023, in Erlanger Ky. More than 1,000 union members at DHL walked off the job at Cincinnati/Northern Kentucky International Airport, a critical logistics hub for the package delivery company, during the busiest time of the year. The Teamsters say they are protesting unfair labor practices at the DHL Express hub. (AP Photo/Carolyn Kaster) NEW YORK -- More than 1,100 unionized DHL Express workers walked off the job at Cincinnati/Northern Kentucky International Airport (CVG), a critical logistics hub for the package delivery company, during the busiest time of the year. The International Brotherhood of Teamsters, which represents over 6,000 DHL workers across the country, said its DHL-CVG members went on strike Thursday to further demand a fair contract and protest unfair labor practices. “For too long, DHL has walked all over our rights to collective action,” Gina Kemp, a DHL-CVG ramp and tug worker, said in a statement shared in the Teamsters' announcement. “This company’s repeated acts of disrespect — from the tarmac where we work to the bargaining table — leave me and my co-workers with no choice but to withhold our labor.” Negotiations between DHL and the Teamsters for a first union contract at CVG began back in July — after ramp and tug workers, who load and unload airplane cargo, voted to organize with the Teamsters in April. In the months since, the union said, the Teamsters have also filed multiple unfair labor practices against DHL with the National Labor Relations Board. In a statement sent to The Associated Press Friday, DHL expressed disappointment over the union's move to “influence these negotiations and pressure the company to agree to unreasonable contract terms by taking a job action in CVG Thursday morning" and said that the company was commited to negotiating in good faith. DHL added the majority of its employees reported to work on Thursday and operations ran at full capacity. The company also said that Teamsters' picket lines were expanded to other U.S. locations on Friday. DHL stated that it anticipated this and has enacted contingency plans — including moving flights and volume to other locations and bringing in replacement staff. A Teamsters spokesperson confirmed to The Associated Press via email on Friday that Local 100 has extended its picket lines to unionized DHL workers in Chicago, the Miami airport gateway and a Covington pickup and delivery operation in Kentucky. These workers are not themselves on strike, the spokesperson said, but are honoring the picket line in solidarity. DHL Express is a unit of Germany’s Deutsche Post AG. In 2022, Deutshe Post AG posted record revenue of over 94 billion euros (more than $101 billion) and operating profit of 8.4 billion euros ($9 billion). DHL's CVG hub is hailed as one of the company's three “global superhubs," alongside operations in Hong Kong and Germany. Its CVG hub sees about 130 daily flights with a 60-aircraft fleet. DHL's CVG workers load and unload roughly 360,000 pounds of cargo each day, the Teamsters said earlier this year. The strike at DHL's CVG hub follows a chain of historic work stoppages and contract negotiations seen over the course of 2023 — from Hollywood and hospitality, to Big Three auto production lines. Hundreds of thousands of workers across the U.S. have participated in labor actions this year.
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The CEO of chipmaker Nvidia views Malaysia as a potential hub for artificial intelligence “manufacturing.” December 8, 2023, 5:30 AM ![Nvidia CEO and co-founder Jensen Huang attends a media round table event at a hotel in Kuala Lumpur, Malaysia Friday, Dec. 8, 2023. (AP Photo/Vincent Thian)](https://i.abcnewsfe.com/a/e3833fe1-1957-4f56-b25d-e47a7527b6cc/wirestory_a55209db56cdd3f85d2b7ea06516cc5d_16x9.jpg?w=992) Nvidia CEO and co-founder Jensen Huang attends a media round table event at a hotel in Kuala Lumpur, Malaysia Friday, Dec. 8, 2023. (AP Photo/Vincent Thian) KUALA LUMPUR, Malaysia -- The CEO of technology giant Nvidia said Friday that he views Malaysia as a potential hub for [artificial intelligence](https://abcnews.go.com/alerts/ArtificialIntelligence) “manufacturing,” though he did not confirm the chipmaker is in talks with a local conglomerate to set up AI data centers in the Southeast Asian country. Jensen Huang, Nvidia’s founder and CEO, told reporters in Kuala Lumpur that the Malaysian conglomerate YTL Corp. could play an important role in setting up AI data centers. Speaking at a media roundtable, Huang did not confirm reports that Nvidia is in talks with YTL, whose interests span utilities and telecommunications, cement, construction and property development. But he said that “YTL is an extraordinary company and has an incredible leadership and legacy.” Malaysia “is a very important hub for SEA’s computing infrastructure. It requires access to land, facilities, power, which is extraordinarily important,” he said. “I think YTL could play a great role in that.” Malaysia’s expertise in packaging, assembly and other aspects of manufacturing make it well suited for the manufacturing of artificial intelligence, Huang said. He said Nvidia was working with 80 AI startups in the country. “Here in Malaysia, the data center infrastructure layer of computing, which is one of the most important parts of the AI and the cloud, is very successful here,” Huang said. Southeast Asia will likely be a hub for AI computing because countries need their own AI data centers to refine and transform data into valuable information. Old data processing centers were designed to hold data files and run applications. AI requires use of each place's culture, language, values, literature and common sense, Huang said. “I don’t know plans of every region well, but I have great confidence that Southeast Asia is going to be a very important technology hub. It’s already quite excellent at packaging and assembly and battery manufacturing. It’s already very good at many aspects of the technology supply chain," he said.